FGF2 Protein
Quick Overview for FGF2 Protein (ABIN2745672)
Target
See all FGF2 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purpose
- FGF-2 (human) (rec.)
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Cross-Reactivity
- Human
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Characteristics
- Human FGF-2 (153aa).
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Endotoxin Level
- <0.1ng/μg protein.
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Biological Activity Comment
- The ED50 for stimulation of cell proliferation in human umbilical vein endothelial cells by human FGF-2 (basic) has been determined to be in the range of 0.1-2 ng/ml.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with sterile water containing at least 0.1 % human or bovine serum albumin to a concentration not lower than 10 μg/mL.
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Buffer
- Contains PBS.
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.
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Expiry Date
- 6 months
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- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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Alternative Name
- FGF-2
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Background
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Basic Fibroblast Growth Factor, bFGF, Heparin Binding Growth Factor-2, HBGF-2
FGF-2 plays an important role in the regulation of angiogenesis, cell survival, cell division, wound healing and tissue repair, embryonic development, cell differentiation and cell migration, neuronal function and neural degeneration. It functions as potent mitogen in vitro.
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Molecular Weight
- ~16.5kDa
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UniProt
- P09038
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
Target
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